PGP9.5 (UCHL1) (NM_004181) Human Recombinant Protein

CAT#: TP720165

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Recombinant protein of human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)



  View other "UCHL1" proteins (5)

USD 300.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC201803, encoding the full length polypeptide (Met1-Ala223) of human UCH-L1
Tag C-His
Predicted MW 25.9 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20mM Tris-HCl, 250mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at -80°C.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_004172
Locus ID 7345
Refseq Size 1141
Cytogenetics 4p13
Refseq ORF 669
Synonyms HEL-117; HEL-S-53; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; SPG79; Uch-L1
Summary The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease. [provided by RefSeq, Sep 2009]
Protein Families Druggable Genome, Protease
Protein Pathways Parkinson's disease

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