Rad6 (UBE2A) (NM_003336) Human Recombinant Protein

CAT#: TP720160

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Recombinant protein of human ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A), transcript variant 1


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USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A), transcript variant 1
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC204194, encoding the full length polypeptide (Met1-Cys152) of human UBE2A
Tag N-His
Predicted MW 49 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_003327
Locus ID 7319
Refseq Size 1878
Cytogenetics Xq24
Refseq ORF 456
Synonyms HHR6A; MRXS30; MRXSN; RAD6A; UBC2
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis

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