Il1a (NM_010554) Mouse Recombinant Protein

CAT#: TP720032

Recombinant protein of mouse interleukin-1a/IL-1a

Product Images

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ser115-Ser270
• Tag: Tag Free
• Predicted MW: 18 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Bioactivity: ED50 is less than 0.01 ng/ml as determined by the dose-dependent stimulation of mouse D10S cells. Specific Activity of 1.0 x 108 IU/mg.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_034684
• Locus ID: 16175
• UniProt ID: P01582, Q3U0Y6
• Cytogenetics: 2 62.9 cM
• Refseq Size: 1974
• Refseq ORF: 813
• Synonyms: Il-1a
• Summary: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.[UniProtKB/Swiss-Prot Function]