GM CSF(CSF2) (NM_000758) Human Recombinant Protein

CAT#: TP720003

Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2)


 Product Datasheet for 'TP720003'

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USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2)
Species Human
Expression Host E.Coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC211109, encoding the mature peptide (Ala18-Glu144 ) of human CSF2/GMCSF
Tag Tag Free
Predicted MW 14.6 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, 5% Mannitol, pH 7.2; Stable for at least 6 months from receipt of products under proper storage and handling conditions.
Bioactivity ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of human TF-1 cell proliferation. Specific Activity of 1.0 x 107 IU/ mg.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_000749
Locus ID 1437
Refseq Size 800
Cytogenetics 5q31.1
Refseq ORF 435
Synonyms GMCSF; GMCSF; CSF
Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
Protein Families Secreted Protein, ES Cell Differentiation/IPS, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Fc epsilon RI signaling pathway

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Other Versions

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    • 100 ul

USD 360.00

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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