VEGF Receptor 1 (FLT1) (NM_002019) Human Recombinant Protein

CAT#: TP710099

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Recombinant protein of human fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1), transcript variant 1, residues 27-758aa, with C-terminal DDK tag, expressed in sf9, 20ug



  View other "FLT1" proteins (2)

USD 425.00


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    • 20 ug


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Product Data
Description Recombinant protein of human fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1), transcript variant 1, residues 27-758aa, with C-terminal DDK tag, expressed in sf9, 20ug
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC224406, encoding the region(Met-Ser27-Glu758) of Homo sapiens FLT1
Tag C-DDK
Predicted MW 82.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002010
Locus ID 2321
Refseq Size 5777
Cytogenetics 13q12.3
Refseq ORF 4014
Synonyms FLT; FLT-1; VEGFR-1; VEGFR1
Summary This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Protein Families Druggable Genome, Protein Kinase, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

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