Estrogen Receptor beta (ESR2) (NM_001437) Human Recombinant Protein

CAT#: TP710031

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Recombinant protein of human estrogen receptor 2 (ER beta) (ESR2), full length, with C-terminal DDK tag, expressed in sf9 cells.


 Product Datasheet for 'TP710031'

 Cited in 1 publication.

  View other "ESR2" proteins (6)

USD 411.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human estrogen receptor 2 (ER beta) (ESR2), full length, with C-terminal DDK tag, expressed in sf9 cells.
Species Human
Expression Host Sf9
Tag C-DDK
Predicted MW 59 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl pH8.0, 100mM glycine, 10% glycerol
Bioactivity Binding assay (PMID: 28842010)
Reference Data
RefSeq NP_001428
Locus ID 2100
Refseq Size 2011
Cytogenetics 14q23.2-q23.3
Refseq ORF 1590
Synonyms ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2; ODG8
Summary This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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