Inhibin beta A (INHBA) (NM_002192) Human Recombinant Protein

SKU
TP701406
Purified recombinant protein of Human inhibin, beta A (INHBA), Gly311-end, tag free, secretory expressed in CHO cells, 10ug
  $900.00
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Specifications
Specifications
Product Data
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC203226, encoding the region Gly311-end of INHBA
Tag Tag Free
Predicted MW 13.0 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 μm filtered solution of 4mM Hcl with trehalose as protectant.
Bioactivity Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 1.84-5.53 ng/mL.
Storage Store at -20°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002183
Locus ID 3624
UniProt ID P08476 A4D1W7
Cytogenetics 7p14.1
RefSeq Size 2175
RefSeq ORF 1278
Synonyms EDF; FRP
Summary This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. provided by RefSeq, Aug 2016
Protein Categories Cytokines, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
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