Annexin V (ANXA5) (NM_001154) Human Recombinant Protein

SKU TP701404

Purified recombinant protein of Human annexin A5 (ANXA5), Ala2-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  1 AQVLRGTVTD FPGFDERADA ETLRKAMKGL GTDEESILTL LTSRSNAQRQ EISAAFKTLF; 61 GRDLLDDLKS ELTGKFEKLI VALMKPSRLY DAYELKHALK GAGTNEKVLT EIIASRTPEE; 121 LRAIKQVYEE EYGSSLEDDV VGDTSGYYQR MLVVLLQANR DPDAGIDEAQ VEQDAQALFQ; 181 AGELKWGTDE EKFITIFGTR SVSHLRKVFD KYMTISGFQI EETIDRETSG NLEQLLLAVV; 241 KSIRSIPAYL AETLYYAMKG AGTDDHTLIR VMVSRSETDL FNIRKEFRKN FATSLYSMIK; 301 GDTSGDYKKA LLLLCGEDDG GGGSHHHHHH HHHH
• Tag: C-HIS
• Predicted MW: 37.5 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_001145
• Locus ID: 308
• UniProt ID: P08758 V9HWE0
• Cytogenetics: 4q27
• RefSeq Size: 1624
• RefSeq ORF: 960
• Synonyms: ANX5; ENX2; HEL-S-7; PP4; RPRGL3
• Summary: The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019]