Tenascin N (TNN) (NM_022093) Human Recombinant Protein

CAT#: TP701099

Purified recombinant protein of Human tenascin N (TNN), Glu29-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug

Product Images

Purified recombinant protein TNN was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC214108, encoding the region Glu29-End of TNN
• Tag: C-HIS
• Predicted MW: 142.3kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH 7.4, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_071376
• Locus ID: 63923
• UniProt ID: Q9UQP3, B3KXB6
• Cytogenetics: 1q25.1
• Refseq Size: 5008
• Refseq ORF: 3897
• Synonyms: TN-W; TNW
• Summary: Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion