ASIP (NM_001672) Human Recombinant Protein

CAT#: TP701037

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Purified recombinant protein of Human agouti signaling protein (ASIP), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug


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USD 748.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human agouti signaling protein (ASIP), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug
Species Human
Expression Host HEK293
Tag C-His
Predicted MW 13.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS,pH7.4,10% glycerol;
Reference Data
RefSeq NP_001663
Locus ID 434
Refseq Size 584
Cytogenetics 20q11.22
Refseq ORF 396
Synonyms AGSW; AGTI; AGTIL; ASP; SHEP9
Summary In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008]
Protein Families Secreted Protein
Protein Pathways Melanogenesis

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