Angiopoietin like 4 (ANGPTL4) (NM_139314) Human Recombinant Protein

CAT#: TP700267

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Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with N-terminal His/DDK tag, expressed in human cells, 20 µg



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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with N-terminal His/DDK tag, expressed in human cells, 20 µg
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC205651, encoding the region (Pro166 – Ser406) of human ANGPTL4
Tag N-His/DDK
Predicted MW 32 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_647475
Locus ID 51129
Refseq Size 1905
Cytogenetics 19p13.2
Refseq ORF 1218
Summary This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways PPAR signaling pathway

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