LGR5 (NM_003667) Human Recombinant Protein

CAT#: TP700187

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Purified recombinant protein of Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), residues 447-561aa, with C-terminal Fc tag, expressed in HEK293 cells.


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USD 748.00


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    • 20 ug


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Product Data
Description Purified recombinant protein of Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), residues 447-561aa, with C-terminal Fc tag, expressed in HEK293 cells.
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC212825, encoding the extracellular domain (His447 - Arg561) of human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5)
Tag C-Fc
Predicted MW 38 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003658
Locus ID 8549
Refseq Size 2880
Cytogenetics 12q21.1
Refseq ORF 2721
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Summary The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, GPCR, Transmembrane

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