CD18 (ITGB2) (NM_001127491) Human Recombinant Protein

CAT#: TP326157

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Purified recombinant protein of Homo sapiens integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2), transcript variant 2


 Product Datasheet for 'TP326157'

 Cited in 2 publications.

  View other "ITGB2" proteins (7)

USD 788.00


Availability*
2 Weeks

Size
    • 20 ug


Product images

Specifications

Product Data
Description Purified recombinant protein of Homo sapiens integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2), transcript variant 2
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 82.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Far-Western blot (PMID: 26600301)
ELISA binding assay (PMID: 29125705)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001120963
Locus ID 3689
Cytogenetics 21q22.3
Refseq ORF 2307
Synonyms CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Summary This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis

Citations (2)

Documents

Other Versions

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