CARS (NM_001014437) Human Recombinant Protein

CAT#: TP324092

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Recombinant protein of human cysteinyl-tRNA synthetase (CARS), transcript variant 3


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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human cysteinyl-tRNA synthetase (CARS), transcript variant 3
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 94.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001014437
Locus ID 833
Refseq Size 2767
Cytogenetics 11p15.4
Refseq ORF 2493
Synonyms CARS1; CYSRS; MGC:11246
Summary This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Protein Families Druggable Genome
Protein Pathways Aminoacyl-tRNA biosynthesis

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