CARS (NM_001014437) Human Recombinant Protein

CAT#: TP324092

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Recombinant protein of human cysteinyl-tRNA synthetase (CARS), transcript variant 3


 Product Datasheet for 'TP324092'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human cysteinyl-tRNA synthetase (CARS), transcript variant 3
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC224092. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 94.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001014437
Locus ID 833
Refseq Size 2767
Cytogenetics 11p15.4
Refseq ORF 2493
Synonyms CARS1; CYSRS; MGC:11246
Summary This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Protein Families Druggable Genome
Protein Pathways Aminoacyl-tRNA biosynthesis

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