Nurr1 (NR4A2) (NM_006186) Human Recombinant Protein

CAT#: TP321280

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Recombinant protein of human nuclear receptor subfamily 4, group A, member 2 (NR4A2)


 Product Datasheet for 'TP321280'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human nuclear receptor subfamily 4, group A, member 2 (NR4A2)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 66.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_006177
Locus ID 4929
Refseq Size 3447
Cytogenetics 2q24.1
Refseq ORF 1794
Synonyms HZF-3; NOT; NURR1; RNR1; TINUR
Summary This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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