Junctional Adhesion Molecule 1 (F11R) (NM_144503) Human Recombinant Protein

CAT#: TP319217

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Recombinant protein of human F11 receptor (F11R), transcript variant 4


 Product Datasheet for 'TP319217'

  View other "F11R" proteins (15)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human F11 receptor (F11R), transcript variant 4
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 33
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_653086
Locus ID 50848
Refseq Size 3861
Cytogenetics 1q23.3
Refseq ORF 900
Synonyms CD321; JAM; JAM-1; JAM-A; JAM1; JAMA; JCAM; KAT; PAM-1
Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction

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Other Versions

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