P2X3 (P2RX3) (NM_002559) Human Recombinant Protein

CAT#: TP318626

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Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3)


 Product Datasheet for 'TP318626'

  View other "P2RX3" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 44.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002550
Locus ID 5024
Refseq Size 1349
Cytogenetics 11q12.1
Refseq ORF 1191
Synonyms P2X3
Summary This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

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