Prostaglandin D Synthase (PTGDS) (NM_000954) Human Recombinant Protein

CAT#: TP316795

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Recombinant protein of human prostaglandin D2 synthase 21kDa (brain) (PTGDS)



  View other "PTGDS" proteins (4)

USD 399.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human prostaglandin D2 synthase 21kDa (brain) (PTGDS)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC216795. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 20.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000945
Locus ID 5730
Refseq Size 837
Cytogenetics 9q34.3
Refseq ORF 570
Synonyms L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
Summary The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
Protein Pathways Arachidonic acid metabolism, Metabolic pathways

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