PAX3 (NM_181457) Human Recombinant Protein

CAT#: TP315181

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Purified recombinant protein of Homo sapiens paired box 3 (PAX3), transcript variant PAX3


 Product Datasheet for 'TP315181'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Homo sapiens paired box 3 (PAX3), transcript variant PAX3
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 52.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_852122
Locus ID 5077
Refseq Size 3193
Cytogenetics 2q36.1
Refseq ORF 1437
Synonyms CDHS; HUP2; WS1; WS3
Summary This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

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