Estrogen Receptor 1(ESR1) (NM_000125) Human Recombinant Protein

CAT#: TP313277

Recombinant protein of human estrogen receptor 1 (ESR1), transcript variant 1

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 Product Datasheet for 'TP313277'

USD 680


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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human estrogen receptor 1 (ESR1), transcript variant 1
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC213277. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 66 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000116
Locus ID 2099
Refseq Size 6456
Cytogenetics 6q25.1-q25.2
Refseq ORF 1785
Synonyms ER; Era; ESR; ESRA; ESTRR; NR3A1
Summary This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Protein Families
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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