AGL (NM_000642) Human Recombinant Protein

CAT#: TP310005

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Recombinant protein of human amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL), transcript variant 1


Product Datasheet for 'TP310005'


  View other "AGL" proteins (19)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 174.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000633
Locus ID 178
Refseq Size 7371
Cytogenetics 1p21.2
Refseq ORF 4596
Synonyms GDE
Summary This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Starch and sucrose metabolism

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Other Versions

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