Cullin 4B (CUL4B) (NM_003588) Human Recombinant Protein

CAT#: TP306935

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Recombinant protein of human cullin 4B (CUL4B), transcript variant 1

 Product Datasheet for 'TP306935'

  View other "CUL4B" proteins (3)

USD 748.00

2 Weeks

    • 20 ug

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Product Data
Description Recombinant protein of human cullin 4B (CUL4B), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 103.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003579
Locus ID 8450
Refseq Size 5365
Cytogenetics Xq24
Refseq ORF 2739
Synonyms CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
Summary This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Pathways Nucleotide excision repair, Ubiquitin mediated proteolysis


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Customer Reviews 
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