TBK1 (NM_013254) Human Recombinant Protein
Recombinant protein of human TANK-binding kinase 1 (TBK1)
Product Datasheet for 'TP305238'
|Description||Recombinant protein of human TANK-binding kinase 1 (TBK1)|
|Predicted MW||83.5 kDa|
|Concentration||>50 ug/mL as determined by microplate BCA method|
|Purity||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Buffer||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol|
|Preparation||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.|
|Synonyms||FTDALS4; IIAE8; NAK; T2K|
|Summary||The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]|
|Protein Families||Druggable Genome, Protein Kinase|
|Protein Pathways||Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.