TBK1 (NM_013254) Human Recombinant Protein

CAT#: TP305238

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Recombinant protein of human TANK-binding kinase 1 (TBK1)


 Product Datasheet for 'TP305238'

  View other "TBK1" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human TANK-binding kinase 1 (TBK1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 83.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_037386
Locus ID 29110
Refseq Size 3098
Cytogenetics 12q14.2
Refseq ORF 2187
Synonyms FTDALS4; IIAE8; NAK; T2K
Summary The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

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Other Versions

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