Prealbumin (TTR) (NM_000371) Human Recombinant Protein

CAT#: TP304976

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Recombinant protein of human transthyretin (TTR)


 Product Datasheet for 'TP304976'

  View other "TTR" proteins (11)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human transthyretin (TTR)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 13.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000362
Locus ID 7276
Refseq Size 938
Cytogenetics 18q12.1
Refseq ORF 441
Synonyms CTS; CTS1; HEL111; HsT2651; PALB; TBPA
Summary This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
Protein Families ES Cell Differentiation/IPS, Secreted Protein

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Other Versions

Frequently bought together (2)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
HUMAN PROREINS 101