Tyrosyl tRNA synthetase (YARS) (NM_003680) Human Recombinant Protein

CAT#: TP304590

Recombinant protein of human tyrosyl-tRNA synthetase (YARS)


 Product Datasheet for 'TP304590'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human tyrosyl-tRNA synthetase (YARS)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC204590. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 59 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003671
Locus ID 8565
Refseq Size 3117
Cytogenetics 1p35.1
Refseq ORF 1587
Synonyms CMTDIC; TYRRS; YRS; YTS
Summary Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Aminoacyl-tRNA biosynthesis

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Other Versions

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