Tyrosyl tRNA synthetase (YARS) (NM_003680) Human Recombinant Protein
Specifications
Product Data | |
Description | Recombinant protein of human tyrosyl-tRNA synthetase (YARS) |
Species | Human |
Expression Host | HEK293T |
Tag | C-Myc/DDK |
Predicted MW | 59 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Reference Data | |
RefSeq | NP_003671 |
Locus ID | 8565 |
Refseq Size | 3117 |
Cytogenetics | 1p35.1 |
Refseq ORF | 1584 |
Synonyms | CMTDIC; TYRRS; YRS; YTS |
Summary | Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Aminoacyl-tRNA biosynthesis |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
AR09995PU-L | Recombinant human YARS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 1,070.00 |
|
PH304590 | YARS MS Standard C13 and N15-labeled recombinant protein (NP_003671) |
USD 1,995.00 |
|
LC418498 | YARS HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
LY418498 | Transient overexpression lysate of tyrosyl-tRNA synthetase (YARS) |
USD 315.00 |
|
AR09995PU-N | Recombinant human YARS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 400.00 |
USD 299.00
USD 360.00