beta TRCP2 (FBXW11) (NM_033644) Human Recombinant Protein
Recombinant protein of human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2
Specifications
Product Data | |
Description | Recombinant protein of human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2 |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC204407. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 60.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_387448 |
Locus ID | 23291 |
Refseq Size | 4536 |
Cytogenetics | 5q35.1 |
Refseq ORF | 1587 |
Synonyms | BTRC2; BTRCP2; FBW1B; Fbw11; FBXW1B; Hos |
Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC409480 | FBXW11 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 110.00 |
|
LC409481 | FBXW11 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 170.00 |
|
LC415862 | FBXW11 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 170.00 |
|
LY409480 | Transient overexpression lysate of F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2 |
USD 360.00 |
|
LY409481 | Transient overexpression lysate of F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1 |
USD 550.00 |
|
LY415862 | Transient overexpression lysate of F-box and WD repeat domain containing 11 (FBXW11), transcript variant 3 |
USD 550.00 |
|
PH304407 | FBXW11 MS Standard C13 and N15-labeled recombinant protein (NP_387448) |
USD 2,260.00 |
USD 350.00
USD 465.00