gamma Catenin (JUP) (NM_002230) Human Recombinant Protein

CAT#: TP304209

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Recombinant protein of human junction plakoglobin (JUP), transcript variant 1


 Product Datasheet for 'TP304209'

 Cited in 1 publication.

  View other "JUP" proteins (8)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human junction plakoglobin (JUP), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC204209. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 81.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Surface Plasmon Ressonance (SPR) (PMID: 29178343)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002221
Locus ID 3728
Refseq Size 3508
Cytogenetics 17q21.2
Refseq ORF 2235
Synonyms ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
Summary This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer

Citations (1)

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