CCR4 NOT transcription complex subunit 3 (CNOT3) (NM_014516) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 81.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055331 |
| Locus ID | 4849 |
| UniProt ID | O75175 |
| Cytogenetics | 19q13.42 |
| RefSeq Size | 2908 |
| RefSeq ORF | 2259 |
| Synonyms | IDDSADF; LENG2; NOT3; NOT3H |
| Summary | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
| Protein Families | Transcription Factors |
| Protein Pathways | RNA degradation |
Reviews
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Resources
| Recombinant Protein Resources |
Other "CCR4 NOT transcription complex subunit 3" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH303795 | CNOT3 MS Standard C13 and N15-labeled recombinant protein (NP_055331) | 10 ug |
$3,360.00
|
|
| LC415218 | CNOT3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415218 | Transient overexpression lysate of CCR4-NOT transcription complex, subunit 3 (CNOT3) | 100 ug |
$436.00
|
|
OriGene AI
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.