Myosin light chain 3 (MYL3) (NM_000258) Human Recombinant Protein

CAT#: TP303122

Recombinant protein of human myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3)

Product images

Specifications

Product Data

• Description: Recombinant protein of human myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3)
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 21.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_000249
• Locus ID: 4634
• Refseq Size: 942
• Cytogenetics: 3p21.31
• Refseq ORF: 585
• Synonyms: CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl
• Summary: MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome
• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)