Myosin light chain 3 (MYL3) (NM_000258) Human Recombinant Protein

CAT#: TP303122

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Recombinant protein of human myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3)


 Product Datasheet for 'TP303122'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 21.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000249
Locus ID 4634
Refseq Size 942
Cytogenetics 3p21.31
Refseq ORF 585
Synonyms CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl
Summary MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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