Cytochrome P450 Reductase (POR) (NM_000941) Human Recombinant Protein

CAT#: TP302172L

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Recombinant protein of human P450 (cytochrome) oxidoreductase (POR)

Size: 20 ug 100 ug 1 mg

USD 9,200.00

8 Weeks*

    • 1 mg

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Frequently bought together (2)
Anti-POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI3H10 (formerly 3H10)
    • 30 ul

USD 200.00

Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
    • 100 ul

USD 412.00


Product Data
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
>RC202172 protein sequence
Red=Cloning site Green=Tags(s)


Tag C-Myc/DDK
Predicted MW 76.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000932
Locus ID 5447
UniProt ID P16435
Cytogenetics 7q11.23
Refseq Size 2509
Refseq ORF 2040
Synonyms CPR; CYPOR; P450R
Summary This gene encodes an endoplasmic reticulum membrane oxidoreductase that is essential for multiple metabolic processes, including reactions catalyzed by cytochrome P450 proteins for metabolism of steroid hormones, drugs and xenobiotics. The encoded protein has a flavin adenine dinucleotide (FAD)-binding domain and a flavodoxin-like domain which bind two cofactors, FAD and FMN, that allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene cause a complex set of disorders, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome, that resemble those caused by defects in steroid metabolizing enzymes such as aromatase, 21-hydroxylase, and 17 alpha-hydroxylase. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, P450, Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.