U1A(SNRPA) (NM_004596) Human Recombinant Protein

CAT#: TP301818

Recombinant protein of human small nuclear ribonucleoprotein polypeptide A (SNRPA)

Bulk Request/Custom Protein Development

 Product Datasheet for 'TP301818'

USD 680.00

In Stock

    • 20 ug

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Product Data
Description Recombinant protein of human small nuclear ribonucleoprotein polypeptide A (SNRPA)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201818. Click on the TrueORF clone link to view cDNA and protein sequences.
Predicted MW 31.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Bioactivity : OriGene human recombinant small nuclear ribonucleoprotein polypeptide A (SNRPA, Cat. #TP301818) was compared side-by-side with baculovirus based insect cell (BEVS) derived SNRPA in a phycoerythrin detecting Luminex assay. The human cell produced SNRPA is comparative or better in sensitivity than the insect cell produced SNRPA to detect autoantibodies in human serum samples.
Reference Data
RefSeq NP_004587
Locus ID 6626
Refseq Size 1626
Cytogenetics 19q13.2
Refseq ORF 846
Synonyms Mud1; U1-A; U1A
Summary The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]
Protein Families
Protein Pathways
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