FUS(FUS) (NM_004960) Human Recombinant Protein

CAT#: TP301808

Recombinant protein of human fusion (involved in t(12;16) in malignant liposarcoma) (FUS)

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 Product Datasheet for 'TP301808'

USD 680.00


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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human fusion (involved in t(12;16) in malignant liposarcoma) (FUS)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201808. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 53.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_004951
Locus ID 2521
Refseq Size 2012
Cytogenetics 16p11.2
Refseq ORF 1578
Synonyms ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS
Summary This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
Protein Families
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