alpha 1 Catenin (CTNNA1) (NM_001903) Human Recombinant Protein

CAT#: TP301766

Recombinant protein of human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1)

Product images

Specifications

Product Data

• Description: Recombinant protein of human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1)
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 99.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_001894
• Locus ID: 1495
• Refseq Size: 3791
• Cytogenetics: 5q31.2
• Refseq ORF: 2718
• Synonyms: CAP102; MDPT2
• Summary: This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction