CYB5R3 (NM_000398) Human Recombinant Protein

CAT#: TP301592

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Recombinant protein of human cytochrome b5 reductase 3 (CYB5R3), transcript variant 1


 Product Datasheet for 'TP301592'

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USD 748.00


Availability*
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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human cytochrome b5 reductase 3 (CYB5R3), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201592. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 34.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000389
Locus ID 1727
Refseq Size 2923
Cytogenetics 22q13.2
Refseq ORF 903
Synonyms B5R; DIA1
Summary This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism

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Other Versions

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