Sodium Potassium ATPase (ATP1A1) (NM_000701) Human Recombinant Protein

CAT#: TP301009

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Recombinant protein of human ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), transcript variant 1



  View other "ATP1A1" proteins (5)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201009. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 112.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000692
Locus ID 476
Refseq Size 3754
Cytogenetics 1p13.1
Refseq ORF 3069
Synonyms MGC3285; MGC51750
Summary The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cardiac muscle contraction

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