Zyxin (ZYX) (NM_001010972) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 61.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001010972 |
| Locus ID | 7791 |
| UniProt ID | Q15942 |
| Cytogenetics | 7q34 |
| RefSeq Size | 2322 |
| RefSeq ORF | 1716 |
| Synonyms | ESP-2; HED-2 |
| Summary | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. provided by RefSeq, Jul 2008 |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Pathways | Focal adhesion |
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Resources
| Recombinant Protein Resources |
Other "Zyxin" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300960 | ZYX MS Standard C13 and N15-labeled recombinant protein (NP_001010972) | 10 ug |
$3,360.00
|
|
| PH314079 | ZYX MS Standard C13 and N15-labeled recombinant protein (NP_003452) | 10 ug |
$3,360.00
|
|
| LC418663 | ZYX HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418663 | Transient overexpression lysate of zyxin (ZYX), transcript variant 1 | 100 ug |
$665.00
|
|
| TP314079 | Recombinant protein of human zyxin (ZYX), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
OriGene AI
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.