GSK3 beta (GSK3B) (NM_002093) Human Recombinant Protein
Recombinant protein of human glycogen synthase kinase 3 beta (GSK3B)
Product Datasheet for 'TP300468'
Specifications
Product Data | |
Description | Recombinant protein of human glycogen synthase kinase 3 beta (GSK3B) |
Species | Human |
Expression Host | HEK293T |
Tag | C-Myc/DDK |
Predicted MW | 47.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Reference Data | |
RefSeq | NP_002084 |
Locus ID | 2932 |
Refseq Size | 1639 |
Cytogenetics | 3q13.33 |
Refseq ORF | 1299 |
Synonyms | glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform |
Summary | The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017] |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Alzheimer's disease, Axon guidance, Basal cell carcinoma, B cell receptor signaling pathway, Cell cycle, Chemokine signaling pathway, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Hedgehog signaling pathway, Insulin signaling pathway, Melanogenesis, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, T cell receptor signaling pathway, Wnt signaling pathway |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
AR51976PU-N |
USD 1,070.00 |
||
AR51976PU-S |
USD 320.00 |
||
AR51323PU-S | Recombinant human GSK3B protein, was expressed in E.coli. |
USD 400.00 |
|
LY431916 | Transient overexpression lysate of glycogen synthase kinase 3 beta (GSK3B), transcript variant 2 |
USD 315.00 |
|
LY419542 | Transient overexpression lysate of glycogen synthase kinase 3 beta (GSK3B), transcript variant 1 |
USD 315.00 |
|
LC419542 | GSK3B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
LC431916 | GSK3B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
PH300468 | GSK3B MS Standard C13 and N15-labeled recombinant protein (NP_002084) |
USD 1,995.00 |
|
LC810097 | GSK3B-knockout Cell lysate from HeLa cell ine, one vial of parental cell line lysate included as control |
USD 495.00 |
|
AR51323PU-N | Recombinant human GSK3B protein, was expressed in E.coli. |
USD 1,070.00 |
|
TP710339 | Purified recombinant protein of Human glycogen synthase kinase 3 beta (GSK3B), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9, 20ug |
USD 411.00 |
USD 299.00
USD 405.00