HPRT (HPRT1) (NM_000194) Human Recombinant Protein

CAT#: TP300462

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Recombinant protein of human hypoxanthine phosphoribosyltransferase 1 (HPRT1)


 Product Datasheet for 'TP300462'

  View other "HPRT1" proteins (7)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human hypoxanthine phosphoribosyltransferase 1 (HPRT1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 24.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000185
Locus ID 3251
Refseq Size 1435
Cytogenetics Xq26.2-q26.3
Refseq ORF 654
Synonyms HGPRT; HPRT
Summary The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. [provided by RefSeq, Jun 2009]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

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Other Versions

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