ROC1 (RBX1) (NM_014248) Human Recombinant Protein

CAT#: TP300348

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Recombinant protein of human ring-box 1 (RBX1)


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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human ring-box 1 (RBX1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 12.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_055063
Locus ID 9978
Refseq Size 906
Cytogenetics 22q13.2
Refseq ORF 324
Synonyms BA554C12.1; RNF75; ROC1
Summary This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5. [provided by RefSeq, Sep 2010]
Protein Families Druggable Genome
Protein Pathways Cell cycle, Nucleotide excision repair, Oocyte meiosis, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway

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