Apc11 (ANAPC11) (NM_001002244) Human Recombinant Protein

CAT#: TP300097

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Recombinant protein of human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1


 Product Datasheet for 'TP300097'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC200097. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 20.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001002244
Locus ID 51529
Refseq Size 1186
Cytogenetics 17q25.3
Refseq ORF 588
Synonyms APC11; Apc11p; HSPC214
Summary Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101