RXR-alpha / RXRA (111-228)

CAT#: SA6040X

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The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.


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USD 620.00


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2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.
Species Human
Expression Host E. coli
Predicted MW 13.6 kDa
Concentration 1.0 mg/ml
Purity > 95 % by SDS-PAGE
Buffer 20 mM Tris-HCl pH 7.5, 0.1 M NaCl, 5 mM beta-Mercaptoethanol
Preparation Liquid protein
Reference Data
RefSeq NP_001278849
Locus ID 6256
Cytogenetics 9q34.2
Synonyms NR2B1
Summary Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer

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68 Mouse Clones