RXR-alpha / RXRA (111-228)
The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.
Product Datasheet for 'SA6040X'
|Description||The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.|
|Expression Host||E. coli|
|Predicted MW||13.6 kDa|
|Purity||> 95 % by SDS-PAGE|
|Buffer||20 mM Tris-HCl pH 7.5, 0.1 M NaCl, 5 mM beta-Mercaptoethanol|
|Summary||Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]|
|Protein Families||Druggable Genome, Nuclear Hormone Receptor, Transcription Factors|
|Protein Pathways||Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer|
|LY401033||Transient overexpression lysate of retinoid X receptor, alpha (RXRA)||
|TP310311||Recombinant protein of human retinoid X receptor, alpha (RXRA)||
|PH310311||RXRA MS Standard C13 and N15-labeled recombinant protein (NP_002948)||
|SA6040||The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.||
|LC401033||RXRA HEK293T cell transient overexpression lysate (as WB positive control)||