PLA2G2A (His-tagged Fusion Protein)

CAT#: PA521X

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Total 140 AA. MW: 15.8 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).


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USD 505.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Total 140 AA. MW: 15.8 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Species Human
Expression Host E. coli
Tag His-tag
Concentration 0.5 mg/mL
Purity > 95 % >95%
Buffer 0.05M Acetate buffer pH4
Preparation Lyophilized purified protein
Reference Data
RefSeq NP_000291
Locus ID 5320
Cytogenetics 1p36.13
Synonyms MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
Summary The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene. [provided by RefSeq, Sep 2009]
Protein Families Druggable Genome, Transmembrane
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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68 Mouse Clones