PLA2G1B (His-tagged Fusion Protein) Human Protein

CAT#: PA520X

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PLA2G1B (His-tagged Fusion Protein) human protein, 0.1 mg



USD 505.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description PLA2G1B (His-tagged Fusion Protein) human protein, 0.1 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFL LDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAI CFSKAPYNKA HKNLDTKKYC QS
Tag His-tag
Concentration 0.5 mg/ml
Purity >95% > 95%
Buffer Presentation State: Purified
State: Lyophilized (0.4 um filtered) purified protein.
Buffer System: 0.05M Acetate buffer pH4
Reconstitution Restore with 0.1M Acetate buffer pH4
Preparation Lyophilized (0.4 um filtered) purified protein.
Applications Western Blot.
Protein Description Total 142 AA. MW: 16 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Note Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C.
Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000919
Locus ID 5319
Cytogenetics 12q24.31
Synonyms PLA2; PLA2A; PPLA2
Summary This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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