Agouti-related protein / AGRP Human Protein

CAT#: PA503X

Agouti-related protein / AGRP human protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MKHHHHHHHM LVPRGSAQMG LAPMEGIRRP DQALLPELPG LGLRAPLKKT TAEQAEEDLL QEAQALAEVL DLQDREPRSS RRCVRLHESC LGQQVPCCDP CATCYCRFFN AFCYCRKLGT AMNPCSRT
• Concentration: lot specific
• Purity: >95%
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Lyophilized purified protein
  Buffer System: 5 mM TRIS, 25 mM NaCl, pH 7.5
• Reconstitution: Restore with deionized water
• Preparation: Lyophilized purified protein
• Applications: ELISA.
  Western Blot.
• Protein Description: Total 128 AA. MW: 14.4 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
• Storage: Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C.
  Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001129
• Locus ID: 181
• UniProt ID: O00253, C6SUN5
• Cytogenetics: 16q22.1
• Synonyms: AGRT; ART; ASIP2
• Summary: This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Adipocytokine signaling pathway