Adiponectin (biologically active)

CAT#: PA500X

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Human Adiponectin
Total 226 AA, UniProt Q15848 (Glu19 – Asn244)


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USD 600.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Human Adiponectin
Total 226 AA, UniProt Q15848 (Glu19 – Asn244)
Species Human
Expression Host HEK293
Concentration 0.5 mg/mL
Purity > 98 % >98%
Buffer 20mM Tris buffer, 20 mM NaCl, pH 7.5
Bioactivity In vitro gluconeogenesis assay in primary hepatocytes was performed, showing the human adiponectin derived from mammalian cells can inhibit glucose production. The ED50 was ~6 µg/ml.
Reconstitution Restore with deionized water
Preparation Lyophilized purified Protein
Reference Data
RefSeq NP_001171271
Locus ID 9370
Cytogenetics 3q27.3
Synonyms ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28
Summary This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Type II diabetes mellitus

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68 Mouse Clones