VEGFR-3 / Flt-4 (His-tagged) Human Protein

CAT#: DA3535S

VEGFR-3 / Flt-4 (His-tagged) human recombinant protein, 5 µg

Specifications

Product Data

• Species: Human
• Expression Host: Insect
• Tag: His-tag
• Predicted MW: 120 kDa
• Purity: >90% by SDS-PAGE and visualised by silver stain
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Lyophilized without buffer and stabilizer.
• Bioactivity: Biological: Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay.
  Immobilised recombinant human sVEGFR-3/FLT-4 at 5 µg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml.
• Endotoxin: < 0.1 ng per µg of sVEGFR-3
• Reconstitution: Restore in PBS or medium to a concentration not lower than 100 µg/ml.
• Preparation: Lyophilized without buffer and stabilizer.
• Protein Description: The recombinant mature sVEGFR-3/FLT-4 is a glycosylated monomeric protein with a mass of approximately 120 kDa. The soluble receptor protein consists of all 7 extracellular domains (Met1-Glu774).
• Note: Centrifuge vials before opening!
• Storage: Prior to and following reconstitution store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001341918
• Locus ID: 2324
• Cytogenetics: 5q35.3
• Synonyms: CHTD7; FLT-4; FLT41; LMPH1A; LMPHM1; PCL; VEGFR-3; VEGFR3
• Summary: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Focal adhesion