Alpha-1-antitrypsin Human Protein
|Description||Alpha-1-antitrypsin human protein, 1 mg|
|Concentration||4.65 mg/ml (OD280nm, E0.1% = 0.433) (prior to lyophilization)|
|Purity||>95% by SDS-PAGE|
|Buffer||Presentation State: Purified
State: Lyophilized purified fraction.
Buffer System: 30mM Sodium Phosphate, pH 6.5 containing 300mM Sodium Chloride without preservatives.
|Reconstitution||Restore with 434.0 µl distilled water.|
|Preparation||Lyophilized purified fraction.|
|Applications||Specific methodologies have not been tested using this product.|
|Protein Description||Human Alpha 1-Antitrypsin.
An acute phase plasma protein found at 290 mg per 100 ml that functions as a protease inhibitor
|Note||Caution: All human source materials have tested negative for HIV 1 and HIV 2 antibodies and non-reactive for anti-HCV, anti-HBc and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.|
|Storage||Upon receipt, Store at -20°C.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Synonyms||A1A; A1AT; AAT; alpha1AT; nNIF; PI; PI1; PRO2275|
|Summary||The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein|
|Protein Pathways||Complement and coagulation cascades|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.