Alpha-1-antitrypsin Human Protein

Alpha-1-antitrypsin human protein, 1 mg

USD 250.00

5 Days

    • 1 mg

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Product Data
Description Alpha-1-antitrypsin human protein, 1 mg
Species Human
Protein Source Plasma
Concentration 4.65 mg/ml (OD280nm, E0.1% = 0.433) (prior to lyophilization)
Purity >95% by SDS-PAGE
Buffer Presentation State: Purified
State: Lyophilized purified fraction.
Buffer System: 30mM Sodium Phosphate, pH 6.5 containing 300mM Sodium Chloride without preservatives.
Reconstitution Restore with 434.0 µl distilled water.
Preparation Lyophilized purified fraction.
Applications Specific methodologies have not been tested using this product.
Protein Description Human Alpha 1-Antitrypsin.
An acute phase plasma protein found at 290 mg per 100 ml that functions as a protease inhibitor
Note Caution: All human source materials have tested negative for HIV 1 and HIV 2 antibodies and non-reactive for anti-HCV, anti-HBc and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage Upon receipt, Store at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000286
Locus ID 5265
Cytogenetics 14q32.13
Synonyms A1A; A1AT; AAT; alpha1AT; nNIF; PI; PI1; PRO2275
Summary The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Complement and coagulation cascades


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