Cardiac Troponin T

Purified Human cardiac Troponin T, also known as cTnT. Immunological identity has been confirmed by reaction with a monoclonal antibody specific for Troponin T cardiac isoform.


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USD 475.00


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5 Days

Size
    • 50 ug


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Specifications

Product Data
Description Purified Human cardiac Troponin T, also known as cTnT. Immunological identity has been confirmed by reaction with a monoclonal antibody specific for Troponin T cardiac isoform.
Species Human
Expression Host Cardiac muscle
Concentration 1.0 mg/ml (Total)
Purity > 98 % pure by SDS-PAGE
Buffer Urea/Tris buffer, pH 7.5 (7 M Urea, 5 mM EDTA, 15 mM Mercaptoethanol, 20 mM Tris)
Preparation Liquid purified protein
Reference Data
RefSeq NP_000355
Locus ID 7139
Cytogenetics 1q32.1
Synonyms CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Summary The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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68 Mouse Clones