Neurofilament M (160 kD) Bovine Protein

CAT#: BA1013

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Neurofilament M (160 kD) bovine protein, 0.25 mg


Product Datasheet for 'BA1013'


USD 405.00


Availability*
2 Weeks

Size
    • 250 ug


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Specifications

Product Data
Description Neurofilament M (160 kD) bovine protein, 0.25 mg
Species Bovine
Protein Source Spinal Cord
Predicted MW 160 kDa
Concentration 1.0 mg/ml (according to Bradford)
Purity >98% (determined by SDS gelelectrophoresis)
Buffer Presentation State: Purified
State: Lyophilized
Reconstitution BA1013: Restore with 200 µl distilled water (final volume 250 μl).
BA1013S: Restore with 80 µl distilled water (final volume 100 µl).
Final solution: 10mM Sodium Phosphate, pH 7.5, 2mM DTT, 6M Urea, 1 mM EDTA.
Preparation Lyophilized
Applications Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protein Description Bovine Neurofilament 160 kDa
Note Isoelectric Point: pI 5.1
Storage Store at 2-8°C (lyophilized) and at -20°C (reconstituted).
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001099011
Locus ID 4741
Cytogenetics 8p21.2
Synonyms NEF3; NF-M; NFM
Summary Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Protein Pathways Amyotrophic lateral sclerosis (ALS)

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