Peroxiredoxin-1 / PRDX1 (1-199, His-tag) Mouse Protein

CAT#: AR52067PU-N

Peroxiredoxin-1 / PRDX1 (1-199, His-tag) mouse protein, 50 µg

Product Images

Specifications

Product Data

• Species: Mouse
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVNK SKEYFSKQKL EHHHHHH
• Tag: His-tag
• Predicted MW: 23.2 kDa
• Concentration: lot specific
• Purity: >90% by SDS - PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Bioactivity: Specific: Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25°C for minute.
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Preparation: Liquid purified protein
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
  
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_035164
• Locus ID: 18477
• UniProt ID: P35700
• Cytogenetics: 4 53.28 cM
• Synonyms: MSP23; NkefA; OSF-3; OSF3; PAG; Paga; PrdxI; prx1; PrxI; Tdpx2; TDX2; TPxA
• Summary: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (PubMed:19766572).[UniProtKB/Swiss-Prot Function]